Related Experiment Video
Updated: Jan 29, 2026
14:15
Measurement Of Neuromagnetic Brain Function In Pre-school Children With Custom Sized MEG
Published on: February 19, 2010
17.3K
Brain Structure and Function in School-Aged Children With Sluggish Cognitive Tempo Symptoms
Ester Camprodon-Rosanas1, Jesus Pujol2, Gerard Martínez-Vilavella3
1Children and Adolescent Mental Health Research Group, Institut de Recerca Sant Joan de Déu, and the Child and Adolescent Psychiatry Hospital Sant Joan de Déu of Barcelona, Spain.
Journal of the American Academy of Child and Adolescent Psychiatry
|February 11, 2019
Summary
Sluggish cognitive tempo (SCT) in children is linked to distinct brain differences. These findings suggest SCT may be a separate attention disorder from ADHD, with unique neural underpinnings.
Area of Science:
- Neuroscience
- Child Psychology
- Developmental Disorders
Background:
- Sluggish cognitive tempo (SCT) is a symptom cluster linked to functional impairments.
- SCT may represent a distinct attention disorder separate from attention-deficit/hyperactivity disorder (ADHD).
- Limited research exists on the neural basis of SCT in children.
Purpose of the Study:
- To investigate the association between SCT symptoms and brain structure and function in school-aged children.
- To differentiate the neural correlates of SCT from those of ADHD.
Main Methods:
- Cross-sectional magnetic resonance imaging (MRI) study of 178 children (8–12 years old).
- Assessment of regional brain volume, white matter integrity (diffusion tensor imaging), and neural network functional connectivity.
- Utilized the Sluggish Cognitive Tempo-Child Behavior Checklist (SCT-CBCL) for symptom evaluation.
Main Results:
- SCT symptoms correlated with increased frontal lobe regional volume.
- These enlarged cortical regions exhibited less mature functional connectivity.
- Anatomical and functional anomalies persisted after controlling for ADHD symptom scores.
Conclusions:
- SCT symptoms are associated with unique brain structure and function characteristics.
- These neural features differ from those previously identified in ADHD.
- Findings support SCT as a distinct neurodevelopmental condition.
Related Concept Videos
01:30Negative and Cognitive Symptoms of Schizophrenia
546
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
546
01:56Structural Protein Function
29.9K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...
29.9K
01:56Structural Protein Function
3.3K
3.3K
01:58Fruit Development, Structure, and Function
25.2K
Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
25.2K
01:38Cognitive Dissonance
37.5K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
37.5K
01:29Structure and Function of Erythrocytes
5.8K
There are between 4.2 and 6 million erythrocytes, also known as red blood cells, in every microliter of blood. These cells are small, flattened biconcave discs with centers that are depressed.
The erythrocyte plasma membrane is associated with proteins such as spectrin, which forms a flexible cytoplasmic meshwork. This meshwork allows erythrocytes to twist, turn, become cup-shaped, and regain their biconcave shape as they pass through narrow capillaries. Additionally, erythrocytes can form...
The erythrocyte plasma membrane is associated with proteins such as spectrin, which forms a flexible cytoplasmic meshwork. This meshwork allows erythrocytes to twist, turn, become cup-shaped, and regain their biconcave shape as they pass through narrow capillaries. Additionally, erythrocytes can form...
5.8K