Neurological Complications of Cardiological Interventions
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Updated: Jan 29, 2026

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Published on: December 23, 2022
Amir Shaban1, Enrique C Leira2,3,4
1Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins drive, Iowa City, IA, 52242, USA. Amir-shaban@uiowa.edu.
Insights
Neurological complications after cardiac procedures are common. Early recognition and expanded treatment windows for stroke improve patient outcomes.
Area of Science:
- Cardiology
- Neurology
- Neurosurgery
Background:
- Neurological complications frequently occur following cardiac procedures.
- The specific cardiac procedure impacts the type and management of neurological complications.
Purpose of the Study:
- To review neurological complications after cardiac procedures.
- To discuss treatment strategies for these complications.
Main Methods:
- Review of current literature on periprocedural neurological complications.
- Analysis of recent clinical trials expanding stroke treatment eligibility.
Main Results:
- Expanded time windows for mechanical thrombectomy and intravenous thrombolysis offer more treatment options for periprocedural strokes.
- Advanced neuroimaging aids in patient selection for stroke interventions.
- Limited data exists on managing cerebrovascular complications in patients with left ventricular assist devices or mechanical valves.
Conclusions:
- Early identification of neurological complications, especially stroke, is crucial for effective treatment.
- Advances in stroke intervention provide increased opportunities for managing periprocedural strokes.
- Further research is needed for cerebrovascular complication management in specific patient populations.
Purpose Of Review:
Neurological complications are common during cardiac procedures. The type of procedure influences the profile of neurological complications and their management. In this article, we review the different neurological complications encountered following cardiac procedures, and treatment strategies for managing those complications.
Recent Findings:
Recent clinical trials have expanded the time window of eligibility for mechanical thrombectomy and intravenous thrombolysis. As a result, more options are now available for the treatment of periprocedural strokes. Early recognition of neurological complications, particularly stroke, will allow more patients to be treated effectively. The expanded window for intravenous thrombolysis and mechanical thrombectomy using advanced neuroimaging for selection provides more opportunities for treatment of periprocedural stroke. There is a paucity of data on the management of cerebrovascular complications, such as ischemic and hemorrhagic strokes, in the setting of left ventricular assist device or mechanical valve.
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