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Updated: Jan 29, 2026

Targeted in Situ Mutagenesis of Histone Genes in Budding Yeast
Published on: January 26, 2017
Analysis of the Teashirt Target Genes in Ureteric Bud Development
Laurent Fasano1, Irene Sanchez-Martin2, Xavier Caubit2
1Aix Marseille University, CNRS, IBDM, Marseille, France. laurent.fasano@univ-amu.fr.
Abstract:
Microarrays and RNA-seq (RNA sequencing) are powerful techniques to assess transcript abundance in biological samples and to improve our understanding of the relationship between genotype and phenotype. Tshz3+/- heterozygous mouse is a model for a human 19q12 syndrome characterized by autistic traits and renal tract defects (Caubit et al., Nat Genet 48:1359-1369, 2016). To unravel renal tract pathological mechanisms, we took advantage of Tshz3 mouse and performed comparative genome-wide expression profiling on embryonic ureter and/or kidney.
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