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Published on: May 23, 2025
Combined Surgical and Endoscopic Approach for Ring-Sling Complex
Giulio Porcedda1, Alice Brambilla1, Silvia Favilli1
1Department of Pediatric Cardiology, Anna Meyer Children Hospital, Florence, Italy.
Insights
Pulmonary artery sling (PAS) with tracheal stenosis (TS) in children is complex. Surgical repair shows an 18% late mortality but good LPA flow, emphasizing multidisciplinary care.
Area of Science:
- Pediatric Surgery
- Cardiovascular Surgery
- Thoracic Surgery
Background:
- Pulmonary artery sling (PAS) is a rare congenital anomaly often associated with long-segment tracheal stenosis (TS).
- High mortality rates in operated children are linked to severe tracheal hypoplasia and congenital heart defects (CHDs).
- This study focuses on the treatment and outcomes of pediatric patients with PAS and severe tracheobronchial involvement.
Purpose of the Study:
- To report the treatment experience and follow-up of pediatric patients with PAS and severe tracheobronchial involvement.
- To analyze the impact of associated CHDs and tracheal hypoplasia on patient outcomes.
- To evaluate the role of respiratory endoscopy in managing these complex cases.
Main Methods:
- Eleven children with PAS and congenital TS underwent surgical intervention between 2005 and 2017.
- Diagnostic tools included echocardiography, computed tomography, and bronchoscopy.
- Tracheal reconstruction involved slide tracheoplasty, with or without cartilage grafts, and LPA reimplantation.
Main Results:
- A late mortality rate of 18% was observed over a mean follow-up of 30 months; no early deaths occurred.
- All patients demonstrated good flow through the LPA post-surgery.
- Ten children required multiple operative bronchoscopies for stent management, granuloma treatment, and dilatation.
Conclusions:
- Severe tracheobronchial stenosis and CHDs significantly influenced hospitalization and the need for repeated endoscopic procedures.
- Management of the PAS/TS complex necessitates specialized centers with multidisciplinary teams.
- Respiratory endoscopy is crucial for both pre-operative assessment and post-operative care in these patients.
Background:
Left pulmonary artery (LPA) sling (PAS) is a vascular ring, which is frequently associated with long-segment tracheal stenosis (TS). Mortality rate in operated children is still high, especially in cases of severe tracheal hypoplasia and/or associated congenital heart defects (CHDs). We report our experience of treatment and follow-up in a pediatric cohort of patients affected by PAS with severe tracheobronchial involvement.
Methods:
From 2005 to 2017, we enrolled 11 children diagnosed with PAS and congenital TS requiring surgical intervention. Echocardiography, computed tomography, and bronchoscopy were performed in all patients. Associated CHD were present in 5 (45%) patients. Tracheal reconstruction techniques included slide tracheoplasty (7/11; 63%), slide tracheoplasty and costal cartilage graft (2/11; 18%), and Hazekamp technique (2/11; 18%).Nine patients underwent LPA direct reimplantation and concomitant tracheoplasty; concomitant surgical repair for CHD was performed in three children.
Results:
Over a mean follow-up of 30 months (range: 3-75 months), a late mortality of 18% was registered; no early death occurred. Good flow through LPA could be documented in all patients. Ten children required operative bronchoscopies (mean: 16/patients) aimed at stent positioning/removal, treatment of granulomas, and tracheobronchial dilatation.
Conclusions:
Severe tracheobronchial stenosis and associated CHD were the main determinants for hospitalization time, intensive assistance, and repeated endoscopic procedures.Patients affected by PAS/TS complex require a careful management at high-specialized centers providing multidisciplinary team.Respiratory endoscopy may play a central role both in preoperatory assessment and in postoperative management of patients showing severe tracheobronchial involvement.
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