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Updated: Jan 29, 2026

Synthesis, Characterization, and Functionalization of Hybrid Au/CdS and Au/ZnS Core/Shell Nanoparticles
Published on: March 2, 2016
Facile Synthesis and In Vitro Biological Screening of Pd@SiO₂ Core-Shell Nanoparticles
K Rajasekar1, A Dinesh2, M Durka3
1Postgraduate and Research Department of Zoology, Khadir Mohideen College, Adirampattinam, Thanjavur 614701, Tamil Nadu, India.
Abstract:
In this study, semiconductor core-shell Pd@SiO₂ nanoparticles (NPs) were prepared by Stober's method. The prepared final products were characterized by XRD, FT-IR, SEM, HR-TEM and EDX techniques. Cell viability of Pd@SiO₂ NPs against HeLa cell line was screened by MTT assay. The present study indicates that the core-shell Pd@SiO₂ NPs are extremely stable along with very high photodynamic efficiency under LED light illumination. The antibacterial activities of core- shell Pd@SiO₂ NPs were determined with Escherichia coli and Staphylococcus aureus by agar diffusion method. DNA binding affinity of the core-shell Pd@SiO₂ NPs towards CT-DNA was also investigated. The observed results showed that SiO₂ supported on the surface of Pd NPs not only prevented aggregation, but also proved the enhanced antimicrobial and DNA binding propensities than the free Pd NPs.
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