Related Experiment Video

Updated: Jan 29, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

Published on: February 9, 2011

23.6K

Absence of the mecC gene in methicillin-resistant Staphylococcus aureus isolated from various clinical samples: The

Aytekin Cikman1, Merve Aydin2, Baris Gulhan1

  • 1Erzincan Binali Yildirim University, Faculty of Medicine, Department of Medical Microbiology, Erzincan, Turkey.

Journal of Infection and Public Health
|February 13, 2019
PubMed
Abstract

Insights

The mecC gene was not detected in any Turkish methicillin-resistant Staphylococcus aureus (MRSA) strains. This study confirms mecA gene prevalence in MRSA, providing a baseline for future surveillance of antibiotic resistance.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Genetics

Background:

  • Methicillin resistance in Staphylococcus aureus (MRSA) is primarily mediated by the mecA gene.
  • A recently identified homolog, the mecC gene, has been reported in some mecA-negative MRSA strains.
  • The prevalence of mecC in MRSA strains across different regions of Turkey remains largely uncharacterized.

Purpose of the Study:

  • To investigate the presence and prevalence of both mecC and mecA genes in MRSA strains isolated from diverse geographical regions in Turkey.
  • To establish a baseline for understanding the genetic basis of methicillin resistance in Turkish MRSA isolates.

Main Methods:

  • Analysis of 494 MRSA strains collected from 17 centers across seven Turkish regions between 2013 and 2016.
  • Determination of methicillin resistance using cefoxitin disk diffusion and oxacillin agar dilution methods.
  • Detection of mecC and mecA genes via Polymerase Chain Reaction (PCR).

Main Results:

  • The mecC gene was not detected in any of the analyzed MRSA strains.
  • The mecA gene was present in 63.8% of the MRSA strains.
  • Staphylococcal Cassette Chromosome mec (SCCmec) typing revealed a predominance of type II (58.7%) and type IV (32.4%) among the characterized strains.

Conclusions:

  • This multi-centered study is the first to comprehensively screen Turkish MRSA strains for the mecC gene.
  • The absence of mecC suggests it is not a significant contributor to methicillin resistance in the studied Turkish MRSA population.
  • The findings underscore the continued importance of the mecA gene in MRSA and provide crucial data for ongoing surveillance of antibiotic resistance in Turkey.
Keywords:
Methicillin resistanceStaphylococcus aureusTurkeymecAmecC

More Related Videos

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus09:03

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

12.4K
Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

17.6K

Related Concept Videos

Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
11.5K
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
338
Center of Gravity00:58

Center of Gravity

The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
6.7K
Center of Gravity01:15

Center of Gravity

The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
To determine its location, the principle of moments can be utilized by dividing the object into...
2.2K
Gene Families01:57

Gene Families

Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
9.9K
Center of Mass00:59

Center of Mass

The center of mass is the point at which the total mass of an object can be said to be concentrated. It is a fundamental principle in mechanics and physics that applies to all objects regardless of their shape or size. The center of gravity is the point at which an object’s weight appears to be concentrated and can be used to balance the object perfectly.
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...
2.0K