Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

5.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.9K
DNA Damage Can Stall the Cell Cycle02:36

DNA Damage Can Stall the Cell Cycle

3.1K
In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
3.1K
DNA Damage can Stall the Cell Cycle02:36

DNA Damage can Stall the Cell Cycle

10.1K
In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
10.1K
Sensory Functions of the Skin01:16

Sensory Functions of the Skin

8.1K
The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
8.1K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

7.8K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Skin damage by tropospheric ozone.

Dermatologie (Heidelberg, Germany)·2019
Same author

Non-conventional rottlerin anticancer properties.

Archives of biochemistry and biophysics·2018
Same author

Association between Siesta (Daytime Sleep), Dietary Patterns and the Presence of Metabolic Syndrome in Elderly Living in Mediterranean Area (Medis Study): The Moderating Effect of Gender.

The journal of nutrition, health & aging·2017
Same author

Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure.

Mechanisms of ageing and development·2017
Same author

The Interaction Between Human Papillomaviruses and the Stromal Microenvironment.

Progress in molecular biology and translational science·2016
Same author

Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing.

Cancer letters·2016

Related Experiment Video

Updated: Jan 29, 2026

Lung microRNA Profiling Across the Estrous Cycle in Ozone-exposed Mice
07:07

Lung microRNA Profiling Across the Estrous Cycle in Ozone-exposed Mice

Published on: January 7, 2019

6.6K

[Skin damage by tropospheric ozone].

K B Fuks1, B Woodby2, G Valacchi3,4

  • 1IUF - Leibniz-Institut für umweltmedizinische Forschung, Düsseldorf, Deutschland.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|February 13, 2019
PubMed
Summary
This summary is machine-generated.

Ground-level ozone (O3) exposure is linked to skin damage and premature aging. This secondary pollutant poses a public health risk as ozone concentrations rise globally.

Keywords:
Air pollutionOxidative stressPeroxidationSkin agingSkin wrinkling

More Related Videos

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
08:54

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure

Published on: October 22, 2019

9.5K
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.5K

Related Experiment Videos

Last Updated: Jan 29, 2026

Lung microRNA Profiling Across the Estrous Cycle in Ozone-exposed Mice
07:07

Lung microRNA Profiling Across the Estrous Cycle in Ozone-exposed Mice

Published on: January 7, 2019

6.6K
In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure
08:54

In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure

Published on: October 22, 2019

9.5K
Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
08:17

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

11.5K

Area of Science:

  • Environmental Science
  • Dermatology
  • Public Health

Background:

  • Tropospheric ozone (O3) is a secondary pollutant formed in sunlight.
  • O3 exposure is linked to pulmonary, cardiovascular, reproductive, and nervous system issues.
  • The skin's role as a target organ for O3 is increasingly recognized.

Purpose of the Study:

  • To investigate the impact of ambient ozone exposure on skin health.
  • To evaluate the association between O3 levels and skin conditions.
  • To explore O3 as a potential factor in premature skin aging.

Main Methods:

  • Review of experimental evidence on O3 effects on skin.
  • Analysis of time series studies correlating O3 levels with medical visits for skin conditions.
  • Examination of epidemiological data on long-term O3 exposure and skin aging.

Main Results:

  • Experimental data indicate O3 exposure causes skin oxidative damage, reduced antioxidant defense, and inflammation.
  • Acute O3 increases correlate with seeking medical care for skin issues.
  • Preliminary evidence suggests long-term O3 exposure is linked to premature skin aging, independent of other environmental factors.

Conclusions:

  • The skin is a vulnerable organ to ambient ozone exposure.
  • Adverse cutaneous effects of ozone represent a significant public health concern.
  • Rising global O3 concentrations necessitate further research into protective strategies.