Jove
Visualize
Contact Us

Related Concept Videos

Genetic Lingo01:11

Genetic Lingo

Overview
Pedigree Analysis01:35

Pedigree Analysis

Overview
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consecutive PRES and diffuse alveolar hemorrhage in a patient with active lupus nephritis and antiphospholipid antibodies: a case report and systematic literature review.

BMC nephrology·2026
Same author

Socioeconomic status in Behçet's syndrome.

Clinical and experimental rheumatology·2026
Same author

Reply to the comment on: Carotid artery ultrasonography and shear wave elastography in Takayasu's arteritis: a comparative analysis with diabetes mellitus.

Clinical and experimental rheumatology·2026
Same author

Comment on: Prevalence, incidence and geographical distribution of familial Mediterranean fever in Turkey.

Clinical and experimental rheumatology·2026
Same author

Internal carotid artery involvement and stroke risk in Takayasu arteritis: a case-control study.

Rheumatology international·2026
Same author

Efficacy and tolerability of switching from coated to compressed colchicine preparations in patients with Behçet's syndrome.

Rheumatology (Oxford, England)·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 16, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Phenotypes in Behçet's syndrome.

Emire Seyahi1

  • 1Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, 81310, Istanbul, Turkey. eseyahi@yahoo.com.

Internal and Emergency Medicine
|February 13, 2019
PubMed
Summary

Behçet syndrome (BS) is a complex, multi-systemic disorder with varied phenotypes, not a uniform disease. Understanding these distinct phenotypes is key to identifying BS and developing targeted treatments.

Keywords:
Behçet’s syndromeCrohn’s diseaseEthnic differencesNeurological involvementOral ulcersPhenotypesUveitisVenous thrombosis

More Related Videos

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Related Experiment Videos

Last Updated: Jun 16, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
07:50

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Area of Science:

  • Rheumatology
  • Genetics
  • Clinical Medicine

Background:

  • Behçet syndrome (BS) is a multi-systemic disorder with unknown etiology and unique geographic distribution.
  • It presents as a complex condition that resists easy classification into standard disease categories.
  • BS is characterized by diverse phenotypes, including skin-mucosa, joint, eye, vascular, neurological, and gastrointestinal involvement.

Purpose of the Study:

  • To explore the concept of phenotyping in Behçet syndrome.
  • To highlight the importance of understanding distinct phenotypes for diagnosis and treatment.
  • To discuss the implications of geographical variations in disease expression.

Main Methods:

  • Review of existing cluster and association studies.
  • Analysis of demographic and clinical features of different BS phenotypes.
  • Examination of geographical differences in disease manifestation.

Main Results:

  • BS is composed of multiple phenotypes, each with unique characteristics and differing management strategies.
  • Phenotyping is crucial for understanding the heterogeneity of BS.
  • Geographical variations in disease expression support the concept of distinct phenotypic components.

Conclusions:

  • Behçet syndrome is better understood as a collection of distinct phenotypes, rather than a single uniform disease.
  • Analyzing these phenotypes can aid in identifying the disorder and improving treatment strategies.
  • Further research into the genetic determinants of each phenotype is warranted.