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Outcome measures to be considered on asthma in elderly
Sandra Nora González-Díaz1, Rosalaura Virginia Villarreal-Gonzalez1,2, Cindy Elizabeth De Lira-Quezada1,2
1Regional Center of Allergy and Clinical Immunology, Universidad Autonoma de Nuevo León.
Current Opinion in Allergy and Clinical Immunology
|February 13, 2019
Summary
Elderly asthma presents unique challenges due to immunosenescence and age-related physiological changes. Understanding these differences is crucial for improving asthma management in older adults.
Area of Science:
- Pulmonology
- Geriatrics
- Immunology
Background:
- Asthma is a chronic respiratory disease impacting quality of life, particularly in older adults.
- Age-related changes in immune responses (immunosenescence) affect disease presentation and treatment.
- Lung physiology and morphology undergo age-associated alterations contributing to asthma.
Purpose of the Study:
- To outline characteristics distinguishing asthma in elderly adults from other age groups.
- To highlight the impact of aging on asthma pathophysiology and treatment.
- To address the underreporting of symptoms in older asthma patients.
Main Methods:
- This is a review article.
- It synthesizes current knowledge on asthma in the elderly.
- It focuses on age-specific physiological and immunological factors.
Main Results:
- Elderly asthma is influenced by immunosenescence, leading to altered immune responses.
- Age-related lung changes include decreased elastic recoil and reduced respiratory muscle strength.
- Older adults may underreport asthma symptoms due to various underlying factors.
Conclusions:
- Asthma in the elderly is distinct due to immunosenescence and physiological aging.
- Further research is needed to optimize asthma diagnosis and treatment in this population.
- Recognizing age-specific factors is key to improving care for elderly asthma patients.
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