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Updated: Jan 29, 2026

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
[Treatment of secondary ischemic mitral regurgitation: controversial issues]
Donato Mele1, Giovanni Andrea Luisi1, Gabriele Pestelli1
1Centro Cardiologico Universitario e LTTA Centre, Università degli Studi, Ferrara.
Abstract:
The presence of secondary mitral regurgitation is an unfavorable prognostic factor in patients with chronic ischemic heart disease. This type of regurgitation can be treated with medical therapy, cardiac resynchronization therapy, surgically or percutaneously but each strategy has controversial aspects. The purpose of this review is to discuss the most debated issues relative to the various modalities available to treat ischemic secondary mitral regurgitation, highlighting also future perspectives.
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