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Related Concept Videos

Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Valve Prolapse II: Assessment and Management01:22

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular tachycardia.
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...

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Related Experiment Video

Updated: May 28, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

When Mitral Repair Fails: Understanding Recurrence, Risk Factors, and Treatment Choices.

Elisa Mikus1, Mariafrancesca Fiorentino1,2, Diego Sangiorgi1

  • 1Cardiovascular Department, Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy.

Journal of Cardiovascular Development and Disease
|May 26, 2026
PubMed
Summary
This summary is machine-generated.

Timing of mitral valve repair failure impacts reoperation strategies. Early failures often involve leaflet prolapse and allow re-repair, while late failures indicate degeneration, typically requiring valve replacement.

Keywords:
minimally invasive cardiac surgerymitral valve repair or replacementreoperationtime to failure

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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

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Last Updated: May 28, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
08:31

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Valve Disease
  • Surgical Outcomes

Background:

  • Reintervention after mitral valve repair is a clinical challenge.
  • Mechanisms and timing of mitral repair failure are not fully understood.
  • Understanding failure patterns can refine surgical strategies for repeat mitral valve surgery.

Purpose of the Study:

  • To investigate the relationship between the time interval to reoperation and the mechanisms of mitral valve repair failure.
  • To assess how the timing of failure influences the feasibility of repeat mitral valve repair versus replacement.

Main Methods:

  • Retrospective analysis of 194 patients undergoing repeat mitral valve surgery after prior repair.
  • Patients stratified into three groups based on time to reoperation: 0-5 years, 6-10 years, and >10 years.
  • Analysis of failure mechanisms and rates of repeat repair across different time intervals.

Main Results:

  • Mechanisms of mitral repair failure varied significantly with time.
  • Early failures (0-5 years) were predominantly due to recurrent leaflet prolapse (47.8%).
  • Late failures (>10 years) were more commonly associated with mitral stenosis (63.9%), with decreasing rates of successful repeat repair over time.

Conclusions:

  • The timing of mitral valve repair failure is linked to specific failure mechanisms.
  • Early failures are more amenable to repeat mitral valve repair.
  • Late failures often result from structural degeneration, necessitating mitral valve replacement.