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Central Retinal Vein Occlusion Revealing Coeliac Disease
Hana Zoubeidi1, Thouraya Ben Salem1, Imed Ben Ghorbel1
1Department of Internal Medicine, Rabta Hospital, Tunis, Tunisia.
Insights
Coeliac disease (CD) can cause rare thrombosis like central retinal vein occlusion (CRVO) in young adults. A gluten-free diet can reverse CRVO in CD patients, highlighting the importance of considering CD in such cases.
Area of Science:
- Ophthalmology
- Gastroenterology
- Hematology
Background:
- Thrombosis is a known complication of coeliac disease (CD).
- Central retinal vein occlusion (CRVO) is an uncommon manifestation of thrombosis in CD.
- Early diagnosis and management are crucial for preventing vision loss.
Purpose of the Study:
- To report a rare case of CRVO in a young adult with coeliac disease.
- To emphasize the association between CD and unusual thrombotic events.
- To highlight the efficacy of a gluten-free diet in managing CRVO secondary to CD.
Main Methods:
- Case presentation of a 27-year-old female with acute visual loss.
- Diagnosis of CRVO confirmed.
- Coeliac disease diagnosed via endoscopic, immunological, and histological findings.
- Assessment of protein S and protein C levels.
Main Results:
- The patient was diagnosed with CRVO and coeliac disease.
- Low levels of protein S and protein C were observed.
- A gluten-free diet led to a favorable clinical outcome and visual improvement.
Conclusions:
- Coeliac disease should be considered in young individuals presenting with thrombosis, particularly in atypical locations like the retina.
- CRVO in the context of CD may be reversible with a gluten-free diet.
- Further research into the mechanisms of thrombosis in CD is warranted.
Introduction:
Thrombosis has been widely reported in coeliac disease (CD) but central retinal vein occlusion (CRVO) is rarely described.
Case Presentation:
A 27-year-old woman presented with acute visual loss and was diagnosed with CRVO. Her protein S and protein C levels were low and CD was diagnosed on the basis of endoscopic, immunological and histological results. A gluten-free diet resulted in favourable evolution.
Conclusion:
CD should be considered in young patients with thrombosis, especially if in an unusual location. Treatment is based on a gluten-free diet.
Learning Points:
Coeliac disease (CD) should be considered in young patients with central retinal vein occlusion (CRVO).Several mechanisms can cause thrombosis in CD.CRVO in CD is often reversible with a gluten-free diet.
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