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Related Experiment Videos

Hyperglycaemic Hemichorea.

Joana Silva Marques1, Nuno Monteiro1, Ana Nunes1

  • 1Internal Medicine Department of Tondela-Viseu Hospital Centre, Viseu, Portugal.

European Journal of Case Reports in Internal Medicine
|February 14, 2019
PubMed
Summary
This summary is machine-generated.

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Hyperglycaemic hemichorea, a rare movement disorder in uncontrolled diabetes, presents with involuntary movements. Prompt improvement after blood glucose normalization is key for diagnosis.

Area of Science:

  • Neurology
  • Endocrinology
  • Movement Disorders

Background:

  • Hyperkinetic disorders like hemichorea can stem from various conditions, including metabolic issues such as hyperglycemia.
  • Hyperglycemic hemichorea is an uncommon, often misdiagnosed movement disorder characterized by unilateral involuntary movements and basal ganglia lesions.
  • The condition typically improves with normalization of blood glucose levels.

Purpose of the Study:

  • To present a case of hyperglycemic hemichorea in a patient with uncontrolled type 2 diabetes.
  • To highlight the diagnostic challenges and the importance of glycemic control in managing this rare condition.

Main Methods:

  • Case report of a 69-year-old woman with type 2 diabetes presenting with hemichorea.
  • Assessment included blood glucose, HbA1c, head CT, and MRI.
Keywords:
Hemichoreadiabetes complicationsmovement disorders

Related Experiment Videos

  • Treatment involved insulin and haloperidol.
  • Main Results:

    • The patient exhibited hemichorea with significantly elevated blood glucose (349 mg/dl) and HbA1c (10.5%).
    • Cranial imaging (CT and MRI) did not reveal basal ganglia lesions or ischemic changes.
    • Clinical improvement was observed after initiating insulin therapy and haloperidol.

    Conclusions:

    • Hyperglycemic hemichorea is a rare cause of hemichorea requiring further research into its pathophysiology and diagnostic criteria.
    • Clinical improvement following glycemic control is the most critical diagnostic indicator.
    • Larger case series are needed to enhance understanding and establish definitive diagnostic guidelines.