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Randomized control trial comparing the titanium osteosynthesis and the biodegradable osteosynthesis in mandibulotomy
Jian Nan Liu1, Hui Shan Ong1, Ming Yi Wang1
1Department of Oral Maxillofacial-Head & Neck Oncology, Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Head & Neck
|February 14, 2019
Summary
Biodegradable implants are as reliable as titanium for mandibulotomy fixation, even after radiotherapy. Postoperative radiotherapy did not increase complication rates in the biodegradable group, offering a safe alternative.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomaterials Science
- Oncology
Background:
- The clinical performance of biodegradable implants after radiotherapy is not well-documented.
- Assessing the degradation rate and strength of biodegradable implants under postoperative radiotherapy (PORT) is crucial.
Purpose of the Study:
- To compare the reliability of biodegradable implants versus titanium implants for mandibulotomy fixation in patients receiving PORT.
- To evaluate the impact of PORT on the outcomes of biodegradable implants.
Main Methods:
- A prospective randomized controlled trial involving 40 mandibulotomy patients.
- Patients were randomized into titanium and biodegradable implant groups, both receiving PORT.
- Key parameters assessed included mouth opening, occlusal force, bony union, function, and complications.
Main Results:
- No significant differences in mandibular function or occlusal status between groups.
- Biodegradable group showed trends towards better MFIQ and satisfaction scores.
- Titanium group experienced higher rates of plate palpability, removal, and osteoradionecrosis.
Conclusions:
- Biodegradable osteosynthesis is a reliable alternative to titanium for mandibulotomy fixation.
- Postoperative radiotherapy does not elevate complication rates in patients treated with biodegradable implants.
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