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Different prognostic effects of core-binding factor positive AML with Korean AML registry data

Ho-Jin Shin1, Woo-Sung Min2, Yoo Hong Min3

  • 1Division of Hematology-Oncology, Department of Internal Medicine, School of Medicine, Medical Research Institute, Pusan National University Hospital, Busan, South Korea.

Annals of Hematology
|February 14, 2019
PubMed
Summary

Core-binding factor acute myeloid leukemia (CBF-AML) in Asian patients shows unique genetic features and variable outcomes. Del(7q) is a strong predictor of poor outcomes in t(8;21) CBF-AML, highlighting the need for further research.

Keywords:
Acute myeloid leukemiaCore-binding factorCytogeneticsD816 mutationRUNX1/RUNX1T1Stem cell transplantation

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