Related Experiment Video
Updated: Jan 29, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
[Cancer and microbiota in elderly patients: challenges and management]
Guillaume Chapelet1, Anne Sophie Boureau2, Emmanuel Montassier3
1Pole de gérontologie clinique, Centre hospitalier universitaire de Nantes, Nantes, France, EE MiHAR (microbiotes, hôtes, antibiotiques et résistance bactérienne), Institut de recherche en santé (IRS2), Université de Nantes, Nantes, France.
Abstract:
Aging is a major risk factor of cancers. In recent years, several studies highlighted a change in the diversity and the abundance of the intestinal microbiota associated with aging. Moreover, epidemiological studies, experimental and clinical studies have suggested that the microbiota is implicated in cancer physiopathology and could modulate the efficacy and the tolerance of oncological treatments, for example the incidence of gastrointestinal toxicity and infectious disease. In this review, our objective was first to described the main studies that have focused on the composition of the microbiota associated with aging, cancer and during cancer therapies. Second, we discussed challenges and perspectives on cancer management and research, in elderly patients. Finally, we assume that further studies will confirm that the composition of the intestinal microbiota could be considered as a biomarker of frailty that could be used to optimize cancer management in elderly patients.
More Related Videos
Related Concept Videos
Tonsillitis II: Management
Impression Management Techniques I: Managing Appearances
Managing Impressions
Management of Insomnia
Cystic Fibrosis: Management
Sinus disease and chronic...
Angina IV: Management

