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Oral Anticancer Therapy: Management of Drug Interactions
Britny G Rogala1, Margaret M Charpentier1, Michelle K Nguyen2
11 University of Rhode Island, Kingston, RI.
Abstract:
Oral anticancer therapy is increasingly integrated into the care of patients with cancer. Recognition and management of drug-drug interactions (DDIs) is critical to providing efficacious and safe anticancer treatment. DDIs with QTc-prolonging agents, anticoagulants, enzyme inducers and inhibitors, antidepressants, and acid suppressants are commonly encountered with anticancer therapies. Here, we review frequently observed DDIs and outline literature-supported suggestions for their management.
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