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Updated: Jan 29, 2026

Cardiac Magnetic Resonance Imaging at 7 Tesla
Published on: January 6, 2019
Clinical and imaging manifestations of primary cardiac angiosarcoma
Jin-Fen Yu1, Hui Cui2, Guo-Min Ji3
1Magnetic Resonance Room, Ji Nan Zhang Qiu District hospital of TCM, Shan Dong, 250200, China.
Insights
Primary cardiac angiosarcoma typically affects the right atrium and can invade nearby structures. CT imaging reveals characteristic enhancement patterns and potential lung metastases.
Area of Science:
- Radiology
- Oncology
- Cardiovascular Imaging
Background:
- Primary cardiac angiosarcoma is a rare malignancy.
- Understanding its CT imaging features is crucial for diagnosis.
Purpose of the Study:
- To investigate the computed tomography (CT) manifestations of primary cardiac angiosarcoma.
- To correlate CT findings with clinical presentation and outcomes.
Main Methods:
- Retrospective analysis of clinical and CT data from 9 patients with cardiac angiosarcoma.
- Review of CT plain scans and enhanced CT scans, including dynamic cine imaging.
Main Results:
- All lesions were located in the right atrium, with some extending to the tricuspid valve and right ventricle.
- CT showed homogeneous or inhomogeneous density, with heterogeneous centripetal enhancement in most cases.
- Five patients had lung metastases, often with distinct sharp edges.
Conclusions:
- Cardiac angiosarcoma has a predilection for the right atrium and invades adjacent structures.
- CT findings include specific enhancement patterns and malignant effusions.
- Pulmonary metastases often present with ground-glass opacity.
Background:
To investigate the CT manifestations of primary cardiac angiosarcoma.
Methods:
The clinical and CT data for 9 patients with cardiac angiosarcoma were retrospectively analyzed.
Results:
The lesions in all nine cases were located in the right atrium. In two cases, the involved lesion led downward to the tricuspid valve and right ventricle, and the dynamic cine showed that the lesion affected the opening and closing of the tricuspid valve. In three cases, the lesion involvement led to a thickened pericardium, accompanied by pericardial effusions. On CT plain scans, six patients showed homogeneous density, while three showed inhomogeneous density, two of which were associated with bleeding. On enhanced CT scans, seven patients showed heterogeneous centripetal enhancement, and some angiograms showed lesions with tortuous small blood vessels. The remaining two cases showed early stage rapid inhomogeneous enhancement. Five cases showed multiple metastatic nodules in the lungs at the time of initial diagnosis; four of these showed distinct sharp edges in multiple pulmonary nodules.
Conclusions:
Cardiac angiosarcoma has a predilection site and is prone to invading adjacent structures, manifesting as malignant pericardial and pleural effusions. The CT enhancement manifestations are mostly inhomogeneous and centripetal with ground-glass opacity peripheral to the intrapulmonary metastases.
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Clinical Manifestations:

