Related Experiment Video
Updated: Jan 29, 2026

Decellularization of Whole Human Heart Inside a Pressurized Pouch in an Inverted Orientation
Published on: November 26, 2018
49-Year-Old Woman With a Broken Heart
Helder Hernández-Rivera1, Carla Rodríguez-Monserrate1, José Escabí-Mendoza1
1is a senior cardiology fellow, is an internal medicine resident, and is chief of the coronary care unit, all in the Department of Medicine, Cardiology Section at the VA Caribbean Healthcare System in San Juan, Puerto Rico.
Insights
A patient presenting with chest pain was initially diagnosed with acute myocardial infarction. However, advanced imaging revealed apical ballooning syndrome, a distinct cardiac condition.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Severe chest pain is a common emergency department presentation.
- Acute myocardial infarction is a primary concern for chest pain patients.
Purpose of the Study:
- To differentiate apical ballooning syndrome from acute myocardial infarction.
- To highlight the importance of diagnostic imaging in cardiac emergencies.
Main Methods:
- Patient presentation with severe chest pain.
- Initial diagnostic suspicion of acute myocardial infarction.
- Utilized advanced imaging tests for diagnosis.
Main Results:
- Imaging tests excluded acute myocardial infarction.
- Imaging tests confirmed apical ballooning syndrome.
- Diagnosis shifted from myocardial infarction to apical ballooning syndrome.
Conclusions:
- Apical ballooning syndrome can mimic acute myocardial infarction.
- Diagnostic imaging is crucial for accurate cardiac diagnosis.
- Prompt and correct diagnosis ensures appropriate patient management.
Abstract:
After presenting to the emergency department with severe chest pain, this patient was thought to be experiencing acute myocardial infarction until imaging tests revealed apical ballooning syndrome.
Related Concept Videos
Anatomy of the Heart
Anatomy of the Heart
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
Overview of the Heart
The heart's structure...
Conduction System of the Heart
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
Conduction System of the Heart
This system relies on the unique properties of nodal and Purkinje cells:...
Chambers of the Heart
Deoxygenated blood from the body is received in the right...

