Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

973
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
973
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

205
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
205
Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

2.2K
The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
2.2K
Social Foundations of Self I: Play and Game01:24

Social Foundations of Self I: Play and Game

205
The development of self in children is deeply rooted in social interactions, mainly through stages of play and structured games. These stages, outlined by sociologist George Herbert Mead, illustrate how children progressively learn to understand and adopt social roles, forming a cohesive sense of self.The Play Stage: Imitation and Simple Role-TakingIn the early years of childhood, the play stage is characterized by imitative behavior, where children engage in role-playing based on familiar...
205
Gene Therapy00:59

Gene Therapy

27.6K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.6K
Group Therapy01:26

Group Therapy

423
Group therapy is a sociocultural approach to psychological treatment, where individuals with shared psychological challenges come together under the guidance of a mental health professional. This therapeutic modality offers unique opportunities for individuals to connect, share, and grow within the context of a supportive group. By fostering mutual understanding and collaboration, group therapy can address a range of psychological concerns effectively, often complementing or surpassing the...
423

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Re: AI and Technology in Geriatrics: A New Chapter in JAGS.

Journal of the American Geriatrics Society·2026
Same author

Normal glycosylated hemoglobin masking glucose dysregulation in a patient with pancreatic and hematologic disease.

JCEM case reports·2026
Same author

Noninsulinoma Hyperinsulinemic Hypoglycemia Syndrome Emerging Post-Nissen Fundoplication.

JCEM case reports·2026
Same author

Elective Total Hip Arthroplasty: Which Surgical Approach Is Optimal?

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2022
Same author

Current strategies to streamline pharmacotherapy for older adults.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2017
Same author

Estimating the Net Career Income of a Geriatrician and a Nurse Practitioner: Still Want to Be a Doctor?

Southern medical journal·2016
Same journal

A Case Report of Unanticipated Difficult Intubation Due to Posterior Tracheal Angulation.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2026
Same journal

Factors Influencing Outcomes of a Telehealth-Based Physical Activity Program in Older Veterans Postdischarge.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2026
Same journal

Updates in Multiple Sclerosis Imaging.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2026
Same journal

Impact of Retroactive Application of Updated Surveillance Guidelines on Endoscopy Center Capacity at a Large VA Health Care System.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2026
Same journal

The Integration of Extended Reality in Arthroplasty: Reviewing Technological Progress and Clinical Benefits.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2026
Same journal

American Hunger Games: Food Insecurity Among the Military and Veterans.

Federal practitioner : for the health care professionals of the VA, DoD, and PHS·2026
See all related articles

Related Experiment Video

Updated: Jan 29, 2026

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.6K

Testosterone Replacement Therapy: Playing Catch-up With Patients.

William T Sheahan1, Suzanne Quinn Martinez1, Adam G Golden1

  • 1is the medical director for the Home Based Primary Care program; is an endocrinologist; and is the associate chief of staff for Geriatrics & Extended Care; all at the Orlando VAMC. Dr. Martinez and Dr. Golden are both associate professor of internal medicine at the University of Central Florida College of Medicine in Orlando.

Federal Practitioner : for the Health Care Professionals of the VA, Dod, and PHS
|February 16, 2019
PubMed
Summary
This summary is machine-generated.

Primary care providers must weigh the advantages and disadvantages of testosterone replacement therapy for patients with low testosterone. Understanding off-label promotion is crucial for informed patient care and treatment decisions.

More Related Videos

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.8K
Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
07:52

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

Published on: September 10, 2018

9.3K

Related Experiment Videos

Last Updated: Jan 29, 2026

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
11:51

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

15.6K
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

11.8K
Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
07:52

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

Published on: September 10, 2018

9.3K

Area of Science:

  • Endocrinology
  • Primary Care Medicine

Background:

  • Growing patient interest in testosterone replacement therapy (TRT) for low testosterone symptoms.
  • Need for primary care providers (PCPs) to be well-informed about TRT.

Purpose of the Study:

  • To review the established risks and benefits of TRT.
  • To examine the influence of off-label promotion on TRT utilization.

Main Methods:

  • Literature review of clinical trials and observational studies on TRT.
  • Analysis of promotional materials and guidelines regarding TRT.

Main Results:

  • TRT offers benefits for confirmed hypogonadism but carries potential risks.
  • Off-label promotion may encourage inappropriate TRT use.

Conclusions:

  • PCPs require comprehensive knowledge of TRT efficacy and safety.
  • Critical evaluation of promotional claims is essential for appropriate patient management.