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Updated: Jan 29, 2026

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
Published on: April 15, 2022
Multiple Myeloma: Updates on Diagnosis and Management
Sarah Jewell1, Zhifu Xiang1, Anuradha Kunthur1
1is a hematology/oncology fellow, , , and are staff hematologist/oncologists, all in the Division of Hematology/ Oncology, Department of Internal Medicine, at the John L. McClellan Memorial Veterans Hospital in Little Rock, Arkansas. Dr. Xiang and Dr. Mehta are also faculty members at the University of Arkansas for Medical Sciences in Little Rock.
Multiple myeloma treatments like multi-drug regimens and stem cell transplants can extend remission. However, most patients eventually experience relapsed multiple myeloma, indicating a need for further therapeutic strategies.
Area of Science:
- Hematology
- Oncology
- Internal Medicine
Background:
- Multiple myeloma is a cancer of plasma cells.
- Current treatments aim to prolong remission and improve patient outcomes.
Purpose of the Study:
- To evaluate the efficacy of current treatment regimens for multiple myeloma.
- To understand the long-term disease trajectory in patients with multiple myeloma.
Main Methods:
- Review of existing data on two- and three-drug treatment regimens.
- Analysis of outcomes following autologous stem cell transplants.
- Assessment of relapse rates in multiple myeloma patients.
Main Results:
- Two- and three-drug regimens offer extended disease remission.
- Autologous stem cell transplants contribute to longer remission periods.
- Relapse remains a significant challenge for most multiple myeloma patients.
Conclusions:
- Current therapeutic strategies provide valuable remission durations for multiple myeloma.
- The high incidence of relapsed multiple myeloma underscores the need for novel treatment approaches.
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09:41An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
Published on: July 15, 2015
10:04Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
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