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Updated: Jan 29, 2026

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats
Published on: March 7, 2025
Comparison of anatomic and functional success of treatment for retinal detachment with macular involvement between
Paola Brito-Sandoval1, Itzel C Espinosa-Soto1, Juan A Ramírez-Estudillo1
1Servicio de Retina y Vítreo, Fundación Hospital Nuestra Señora de la Luz, I.A.P., Ciudad de México, México.
Objective:
To compare the frequency of anatomic and functional success, between eyes with uncomplicated rhegmatogenous retinal detachment treated with exoplant or vitrectomy.
Method:
Non-experimental, retrospective, comparative and longitudinal study in patients with rhegmatogenous retinal detachment, <20/200 visual acuity and macular involvement, treated with exoplant (group 1) or vitrectomy (group 2), and 9 months follow up, without proliferative vitreoretinopathy or other vitreoretinal disease that reduced vision. The frequencies of anatomic success (attached retina) and functional success (visual acuity > 20/200) were compared between groups at the end of follow up (chi squared and odds ratio).
Results:
114 patients, mean age 48.5 ± 16.6 years, mean detachment duration 49.8 ± 32.0 days; group 1 had 33 subjects (28.9%) and group 2 had 81 (71.1%). Anatomic success was achieved in 27 subjects of group 1 (81.8%; 95% confidence interval [95% CI]: 68.7-95) and in 74 of group 2 (91.4%; 95% CI: 85.2-97.5; p = 0.1); 14 subjects of group 1 (42.4%) and 21 of group 2 (25.9) had functional success (p = 0.1).
Discussion:
In our media, the frequencies of anatomic and functional success after treating rhegmatogenous retinal detachment did not differ between exoplant and vitrectomy. Early detection should be favored, to increase the frequency of postoperative visual improvement.
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