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Updated: Jan 29, 2026

External Cephalic Version: Is it an Effective and Safe Procedure?
Published on: June 6, 2020
A New Suggested Strategy for Safe Injection of Ozurdex
Background And Objectives:
Ozurdex intravitreal injection is performed via a patented injection device. However, there is a common misconception among ophthalmologists regarding the relation between the speed of applicator button depression and the speed of pellet injection.
Patients And Methods:
Six dexamethasone intravitreal implants were injected into a calibrated ex vivo water bath. Three of the pellets were injected via rapid compression, whereas the other three implants were injected using a 3-second compression technique. The procedures were recorded using high-speed photography followed by calculation of pellet velocity and impact force.
Results:
The mean impact velocity and force of the pellet insertion is significantly higher in the fast injection group compared to the slow injection group.
Conclusions:
By depressing the Ozurdex implant injector during a 3-second time interval, the impact force of the implant pellet is reduced by about 95%. This new technique will theoretically reduce the risk of retinal injury and vitreous hemorrhage from Ozurdex injections. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e23-e25.].
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