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Humanized Mediator Release Assay as a Read-Out for Allergen Potency
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Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity
Tanzeela Hanif1, Kishor Dhaygude1, Matti Kankainen2
1Haartman Institute, University of Helsinki, Helsinki, Finland.
The Journal of Allergy and Clinical Immunology
|February 16, 2019
Summary
No abstract available in PubMed .
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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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