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Preliminary Definitions for Sacroiliac Joint Pathologies in the OMERACT Juvenile Idiopathic Arthritis Magnetic
Tarimobo M Otobo1,2, Philip G Conaghan1,2, Walter P Maksymowych1,2
1From the Institute of Medical Sciences, Faculty of Medicine, University of Toronto; Department of Diagnostic Imaging, The Hospital for Sick Children; Department of Translational Medicine, SickKids Research Institute, Peter Gilgan Center for Research and Learning; Dalla Lana School of Public Health, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, University of Toronto; Department of Medical Imaging, University of Toronto; Department of Rheumatology, Center for Prognosis Studies in Rheumatologic Diseases, Toronto Western Hospital, Toronto, Ontario; Department of Rheumatology, University of Alberta; Department of Radiology and Diagnostic Imaging, University of Alberta; Division of Pediatric Rheumatology, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds Teaching Hospitals National Health Service (NHS) Trust, Leeds, UK; Department of Rheumatology, Leiden University Medical Center, Leiden; Reade | Emma Children's Hospital/Academic Medical Center, Amsterdam, the Netherlands; University of Pennsylvania Perelman School of Medicine, Division of Rheumatology, Children's Hospital of Philadelphia and Departments of Pediatric and Epidemiology, Philadelphia, Pennsylvania; Department of Radiology, Nemours Children's Hospital and Health System, Orlando, Florida, USA; Department of Radiology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Department of Radiology and Medical Imaging, Ghent University Hospital, Ghent, Belgium; Department of Radiology, Hospital Sant Joan de Deu, Barcelona, Spain; Department of Radiology, Rikshospitalet, Oslo University Hospital, Oslo, Norway; Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, India; State University of Campina-UNICAMP, Department of Internal Medicine, Cidade Universitaria, Sao Paulo, Brazil.
Objective:
To develop definitions for the assessment of magnetic resonance imaging (MRI) pathologies of the sacroiliac joints (SIJ) in juvenile idiopathic arthritis.
Methods:
An Outcome Measures in Rheumatology (OMERACT) consensus-driven methodology consisting of iterative surveys and focus group meetings within an international group of rheumatologists and radiologists.
Results:
Two domains, inflammation and structural, were identified. Definitions for bone marrow edema, joint space inflammation, capsulitis, and enthesitis were derived for joint inflammation; sclerosis, erosion, fatty lesion, and ankylosis were defined for assessing structural joint changes.
Conclusion:
Preliminary consensus-driven definitions for inflammation and structural elements have been derived, underpinning the ongoing development of the OMERACT Juvenile Arthritis MRI SIJ scoring system (OMERACT JAMRIS-SIJ).
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