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Updated: Jan 29, 2026

Author Spotlight: A Novel Protocol for Intracameral Injections to Enhance Precision in Rodent Ophthalmology
Published on: May 31, 2024
Intracameral Phenylephrine to Arrest Intraoperative Intraocular Bleeding: A New Technique
Mukhtar Bizrah1, Melanie C Corbett2
1The Western Eye Hospital, Imperial College NHS Trust, London, UK. mbizrah@gmail.com.
Intracameral phenylephrine injection effectively stopped anterior chamber bleeding during cataract surgery. This novel approach enabled surgeons to safely complete procedures without further hemorrhage, improving patient outcomes.
Area of Science:
- Ophthalmology
- Surgical Innovation
Background:
- Intraoperative bleeding during anterior segment surgeries like cataract surgery poses significant challenges.
- Uncontrolled bleeding can impede surgical progress and lead to complications.
Purpose of the Study:
- To evaluate the efficacy of intracameral phenylephrine in managing intraoperative anterior chamber bleeding.
- To report the first use of intracameral phenylephrine for hemostasis during cataract surgery.
Main Methods:
- Intracameral injection of phenylephrine was administered in three cases with intraoperative anterior chamber bleeding.
- One case involved concurrent CyPass® Micro-Stent insertion.
Main Results:
- Complete cessation of bleeding was achieved within one minute following phenylephrine injection.
- No intraoperative or postoperative hemorrhage occurred in the treated cases.
Conclusions:
- Intracameral phenylephrine is a safe and effective method for controlling intraoperative anterior chamber bleeding.
- This technique facilitates the safe completion of anterior segment surgeries complicated by bleeding.
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