Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risk assessment and management models in development.

R W Hart1, A Turturro

  • 1National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas 72079.

Biomedical and Environmental Sciences : BES
|June 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased effective activity of rat liver catalase by dietary restriction.

Age·2013
Same author

A circadian study of liver antioxidant enzyme systems of female Fischer-344 rats subjected to dietary restriction for six weeks.

Age·2013
Same author

Point-of-care oral-based diagnostics.

Oral diseases·2011
Same author

Self-organization of polystyrenes into ordered microstructured films and their replication by soft lithography.

Langmuir : the ACS journal of surfaces and colloids·2005
Same author

Assessment and significance of 24-h energy intake patterns among young and aged non-affluent southern US women.

The journal of nutrition, health & aging·2003
Same author

Caloric restriction mimetics: physical activity and body composition changes.

The journals of gerontology. Series A, Biological sciences and medical sciences·2002
Same journal

A Nationwide Analysis of Key Environmental Determinants Shaping the Spatial Distribution of Kashin-Beck Disease in China.

Biomedical and environmental sciences : BES·2026
Same journal

PM <sub>2.5</sub> Exposure-induced Lung Injury in Mice <i>via</i> Ferroptosis.

Biomedical and environmental sciences : BES·2026
Same journal

Compound K Mitigates PM <sub>2.5</sub>-induced Premature Senescence in ARPE-19 Human Retinal Pigment Epithelial Cells through Activation of the Nrf2/HO-1 Pathway.

Biomedical and environmental sciences : BES·2026
Same journal

Evaluating the Roles of PM <sub>2.5</sub> and Its Components in Frailty: An Integration of Epidemiological and Network Toxicological Evidence.

Biomedical and environmental sciences : BES·2026
Same journal

Association of Ambient PM <sub>2.5</sub> Components with Lung Function in Adults Aged 40-89 Years: A Cross-sectional Study in China.

Biomedical and environmental sciences : BES·2026
Same journal

Histopathological Assessment Using SAF Scoring: Investigating Risk Factor Correlations with Disease Severity in MASLD Patients.

Biomedical and environmental sciences : BES·2026
See all related articles

Regulatory toxicology evaluates public and environmental safety from substance exposure. Risk management integrates toxicity data with societal factors like economics and politics to ensure safety.

Area of Science:

  • Toxicology
  • Risk Assessment
  • Public Health

Background:

  • Historically, toxicology focused on poisons and antidotes.
  • Societal needs have driven the development of regulatory toxicology to assess public hazards.
  • Modern toxicology has expanded its scope to include evaluating public health and environmental safety.

Purpose of the Study:

  • To describe the evolution and scope of regulatory toxicology.
  • To explain the process of risk management in ensuring safety.
  • To discuss the factors influencing risk assessment and management.

Main Methods:

  • Review of historical and societal drivers for regulatory toxicology.
  • Explanation of risk assessment methodologies for toxic endpoints.

Related Experiment Videos

  • Discussion of risk management strategies incorporating toxicity, values, politics, and economics.

    • Main Results:

    • Regulatory toxicology has broadened the knowledge base and capacity to alter toxicity.
    • Risk management is a complex process involving scientific data and societal considerations.
    • Understanding public concern is key to effective risk management.

    Conclusions:

    • Regulatory toxicology is essential for evaluating potential hazards of substances.
    • Risk management requires a multidisciplinary approach beyond just toxicity data.
    • Effective management of risks impacts society, public health, and economics.