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Maximizing nuclear hyperpolarization in pulse cooling under MAS.

Snædís Björgvinsdóttir1, Brennan J Walder1, Nicolas Matthey1

  • 1Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|February 18, 2019
PubMed
Summary
This summary is machine-generated.

Dynamic nuclear polarization enhances bulk hyperpolarization in solids. Optimizing pulse cooling with modulated magic angle spinning significantly boosts sensitivity for 119Sn spectra in SnO2.

Keywords:
Cross-polarizationDynamic nuclear polarizationSolid-state NMRSpin diffusion

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Area of Science:

  • Solid-state Nuclear Magnetic Resonance (NMR) spectroscopy
  • Dynamic Nuclear Polarization (DNP)
  • Materials Science

Background:

  • Dynamic nuclear polarization (DNP) enables hyperpolarization of proton-free solids.
  • Bulk hyperpolarization is achieved via surface polarization transfer and spin diffusion.
  • Pulse cooling is a DNP strategy using cross-polarization for bulk hyperpolarization.

Purpose of the Study:

  • To maximize sensitivity in bulk hyperpolarization using the pulse cooling method.
  • To experimentally optimize pulse parameters and delays for enhanced signal detection.
  • To introduce a novel approach for improving sensitivity in solid-state NMR.

Main Methods:

  • Experimental optimization of pulse parameters and delays for pulse cooling.
  • Modulated magic angle spinning (MAS) rate during the experiment.
  • Utilizing slow MAS for efficient spin diffusion and accelerated MAS for line narrowing.

Main Results:

  • Achieved significant sensitivity enhancement for 119Sn spectra in powdered SnO2.
  • Demonstrated a 3.5-fold increase in sensitivity using the optimized pulse cooling method.
  • Validated the effectiveness of modulated MAS in improving signal-to-noise ratios.

Conclusions:

  • The optimized pulse cooling method with modulated MAS substantially improves sensitivity for solid-state NMR.
  • This technique offers a pathway for enhanced detection of weakly magnetic nuclei in bulk solids.
  • Further applications in materials characterization and analysis are anticipated.