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Updated: Jan 29, 2026

Capsular Serotyping of Streptococcus pneumoniae by Latex Agglutination
Published on: September 25, 2014
Cystic lesion caused by latex material.
A tooth cyst refractory to endodontic therapy was treated with surgery. The cause was identified as latex foreign material, likely from a dental glove, with successful resolution observed after treatment.
Area of Science:
- Endodontics
- Oral Pathology
- Dental Materials
Background:
- Cystic lesions associated with teeth can complicate endodontic treatment.
- Refractory periapical lesions may require advanced diagnostic and surgical interventions beyond conventional endodontic therapy.
Purpose of the Study:
- To report the management of a refractory cystic lesion associated with a maxillary second premolar.
- To investigate the etiology of a persistent periapical lesion after initial endodontic treatment.
Main Methods:
- Conventional endodontic therapy was performed on the maxillary second premolar.
- Surgical intervention including cyst enucleation, biopsy, and apical surgery was conducted.
- Histopathological examination of the enucleated lesion was performed.
Main Results:
- Initial endodontic treatment led to incomplete healing of the cystic lesion.
- Histopathology revealed foreign latex material in the periapical tissue, suspected to be from a dental glove.
- Surgical treatment resulted in significant resolution of the lesion at the 1-year follow-up.
Conclusions:
- Refractory periapical cystic lesions may harbor unexpected foreign materials.
- Latex foreign material exposure can lead to persistent inflammatory responses and treatment failure in endodontics.
- Combined endodontic and surgical management, with thorough histopathological analysis, is crucial for refractory cases.
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