[Follow-up recommendations for the late preterm infant]

Mercedes García Reymundo1, José Antonio Hurtado Suazo2, M José Calvo Aguilar3

  • 1Grupo SEN34-36/ACUNA, Sociedad Española de Neonatología, España; Unidad de Neonatología, Hospital Mérida, Mérida, España.

Anales De Pediatria
|February 20, 2019
PubMed

Insights

Late preterm infants (34-36 weeks gestation) face higher risks for developmental issues and hospital readmissions. New guidelines aim to improve their long-term outcomes and early detection of delays.

Area of Science:

  • Neonatology
  • Pediatrics
  • Developmental Neuroscience

Background:

  • Late preterm infants (34-36 weeks gestation) comprise a significant portion of premature births (70-74%).
  • These infants are often managed as term newborns, leading to limited understanding of their medium and long-term outcomes.
  • They exhibit higher neonatal morbidity, including increased hospital readmissions for malnutrition, hyperbilirubinemia, and respiratory issues compared to term infants.

Purpose of the Study:

  • To establish follow-up recommendations for late preterm infants to mitigate the impact of prematurity on development.
  • To raise awareness among neonatologists and pediatricians regarding the risks of sequelae in this population.
  • To standardize evaluations and interventions for early detection of developmental delays and coordinate professional care.

Main Methods:

  • Development of follow-up recommendations by the SEN34-36 Group and the Spanish Association of Primary Care Paediatrics.
  • Focus on identifying and unifying necessary evaluations and interventions.
  • Provision of clinical follow-up tools for early detection of developmental delays.

Main Results:

  • Cerebral immaturity is identified as a primary cause of long-term neurodevelopmental deficits in late preterm infants.
  • Documented long-term issues include preschool developmental delays, cerebral palsy, intellectual disability, schizophrenia, and behavioral/emotional disorders.
  • The guidelines aim to reduce the impact of prematurity on development and improve long-term health outcomes.

Conclusions:

  • Late preterm infants require specific follow-up protocols due to their unique vulnerabilities and potential for neurodevelopmental deficits.
  • Standardized follow-up and early detection tools are crucial for improving the developmental trajectory of these infants.
  • Collaborative care between neonatologists and pediatricians is essential for optimizing the outcomes of late preterm infants.

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
283
Theory of Romantic Attachment in Adulthood03:34

Theory of Romantic Attachment in Adulthood

Attachment is a long-standing connection or bond with others. While Attachment Theory was conceived in developmental psychology to describe infant-caregiver bonding, it's been extended into adulthood to include romantic relationships. 
49.9K
Chromosomal Theory of Inheritance01:39

Chromosomal Theory of Inheritance

In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
60.0K
Social Traps01:41

Social Traps

Social traps are negative situations where people get caught in a direction or relationship that later proves to be unpleasant, with no easy way to back out of or avoid. The concept was orignally introduced by John Platt who applied psychology to Garrett Hardin's "Tragedy of the Commons", where in New England herd owners could let their cattle graze in the common ground. This situation seems like a good idea, but an individual could have an advantage. If they owned...
26.9K
Cause and Effect01:53

Cause and Effect

While variables are sometimes correlated because one does cause the other, it could also be that some other factor, a confounding variable, is actually causing the systematic movement in our variables of interest. For instance, as sales in ice cream increase, so does the overall rate of crime. Is it possible that indulging in your favorite flavor of ice cream could send you on a crime spree? Or, after committing crime do you think you might decide to treat yourself to a cone?
12.2K
Histone Variants at the Centromere02:30

Histone Variants at the Centromere

Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3...
5.0K