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Related Concept Videos

Shock Waves01:16

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While deriving the Doppler formula for the observed frequency of a sound wave, it is assumed that the speed of sound in the medium is greater than the source's speed through it. When this condition is breached, a shock wave occurs.
When the source's speed approaches the speed of sound, constructive interference between successive wavefronts emitted by the source occurs immediately behind it. Initially, scientists believed that this constructive interference would result in such high...
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Disorders affecting blood volume, vascular tone, or vascular function can disrupt vascular homeostasis, including conditions like hypertension, hemorrhage, and shock.
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Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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Obedience to authority is classically demonstrated in a more famous series of social psychology experiments performed by Stanley Milgram. He was a social psychology professor at Yale who was influenced by the trial of Adolf Eichmann, a Nazi war criminal. Eichmann’s defense for the atrocities he committed was that he was “just following orders.”
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Overview
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Related Experiment Video

Updated: Jan 28, 2026

Drosophila Adult Olfactory Shock Learning
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Vasopressin in Vasodilatory Shock.

Ida-Fong Ukor1, Keith R Walley1

  • 1Division of Critical Care Medicine, Centre for Heart Lung Innovation, University of British Columbia, 1081 Burrard Street, Vancouver, British Columbia V6Z 1Y6, Canada.

Critical Care Clinics
|February 21, 2019
PubMed
Summary

Vasodilatory shock, often caused by sepsis, involves vasopressin deficiency. This review explores vasopressin

Area of Science:

  • Critical care medicine
  • Endocrinology
  • Pathophysiology

Background:

  • Vasodilatory shock is a critical condition with high mortality, frequently stemming from sepsis.
  • The underlying pathophysiology, particularly the role of vasopressin, is not fully understood.
  • Vasopressin deficiency is implicated in the progression of vasodilatory shock.

Purpose of the Study:

  • To review the physiology of vasopressin.
  • To examine the role of vasopressin in the pathophysiology of vasodilatory shock.
  • To summarize clinical trials on vasopressin-based therapies for vasodilatory shock.

Main Methods:

  • Literature review of vasopressin physiology and pathophysiology.
  • Analysis of randomized controlled trials (RCTs) involving vasopressin and its analogs.
Keywords:
Antidiuretic hormoneSepsisVasodilatory shockVasoplegiaVasopressin

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  • Synthesis of current evidence on vasopressin's efficacy and safety in severe shock.

    • Main Results:

    • Vasopressin plays a key role in maintaining vascular tone.
    • Deficiency contributes to refractory hypotension in vasodilatory shock.
    • RCTs provide insights into vasopressin's therapeutic potential and limitations.

    Conclusions:

    • Vasopressin is crucial for vascular homeostasis and its deficiency exacerbates vasodilatory shock.
    • Further research and clinical trials are needed to optimize vasopressin-based treatments.
    • Understanding vasopressin's role is vital for managing sepsis-induced shock and improving patient outcomes.