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New Agents for the Treatment of Type 2 Diabetes
Renata Libianto1, Elif I Ekinci2
1Department of Medicine, The University of Melbourne, Austin Health, 300 Waterdale Road, Heidelberg West, Melbourne, Victoria 3081, Australia.
Abstract:
The Renaissance of glucose-lowering therapies has arrived with multiple agents that lower blood glucose and demonstrate cardiovascular and renal benefits in people with type 2 diabetes. This article summarizes these new classes of therapies, including the sodium glucose co-transporter-2 inhibitors, glucagon-like peptide-1 agonists, and dipeptidyl peptidase-4 inhibitors. Their cardiovascular safety profile, effects on glycemic, weight, and renal outcomes are discussed. As more options become available to treat type 2 diabetes, clinicians need to be aware of the advantages of each class of medications, beyond their glycemic lowering effects. The safety profiles are summarized in this article.
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