Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent data on magnesium and osteoporosis.

L Cohen1

  • 1Department of Medicine B, Faculty of Medicine, Technion-Israel Institute of Technology, Lady Davis Carmel Hospital, Haifa, Israel.

Magnesium Research
|July 1, 1988
PubMed
Summary

Postmenopausal osteoporosis is linked to larger bone crystals and lower magnesium levels, suggesting a deficiency possibly due to malabsorption. This impacts bone health and magnesium retention.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CD14-independent responses to LPS require a serum factor that is absent from neonates.

Journal of immunology (Baltimore, Md. : 1950)·1995
Same author

T cell receptor repertoire in the peripheral blood and intestinal mucosa of coeliac patients.

Clinical and experimental immunology·1995
Same author

Suramin and hydrocortisone: determining drug efficacy in androgen-independent prostate cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·1995
Same author

A radiation overdose incident: initial data.

International journal of radiation oncology, biology, physics·1995
Same author

Body dysmorphic disorder in the DSM-IV field trial for obsessive-compulsive disorder.

The American journal of psychiatry·1995
Same author

Seasonal rhythm of platelet [3H]imipramine binding in adolescents who attempted suicide.

The American journal of psychiatry·1995

Area of Science:

  • Bone biology
  • Mineral metabolism
  • Osteoporosis research

Background:

  • Osteoporosis is characterized by compromised bone strength, increasing fracture risk.
  • Bone mineral crystal structure and magnesium content are critical determinants of bone quality.
  • Several types of osteoporosis, including postmenopausal, senile, and alcoholic, are associated with altered bone mineral characteristics.

Purpose of the Study:

  • To investigate the characteristics of bone mineral crystals and magnesium concentration in various osteoporosis types.
  • To explore the potential role of magnesium deficiency and malabsorption in postmenopausal osteoporosis.

Main Methods:

  • Analysis of bone mineral crystal perfection and magnesium concentration in patient samples.
  • Assessment of magnesium retention using a magnesium load test.

Main Results:

  • Larger and more perfect bone mineral crystals were observed across different osteoporosis types.
  • Decreased bone magnesium concentration was a consistent finding in postmenopausal, senile, alcoholic osteoporosis, and thalassaemia-associated osteoporosis.
  • Increased magnesium retention in the magnesium load test indicated potential magnesium deficiency in postmenopausal osteoporosis.

Conclusions:

  • Alterations in bone mineral crystal structure and reduced bone magnesium are associated with multiple forms of osteoporosis.
  • Magnesium deficiency, likely resulting from malabsorption, is implicated in the pathogenesis of postmenopausal osteoporosis.

Related Experiment Videos