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Updated: Jan 28, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Switching from expectorated to induced sputum cultures for tuberculosis diagnosis reduces cost without increasing
Qasim A Mohiuddin1, Leighanne Parkes2, Michael Gardam3
1Infection Prevention and Control, University Health Network, Toronto, ON, Canada.
Abstract:
Active pulmonary tuberculosis testing with 3 expectorated sputa can increase isolation days and expenditures compared with 1 induced sputum. Six-month retrospective and prospective chart reviews were conducted, and a screening algorithm was phased into 2 hospital sites. With induced sputum testing, isolation decreased from 7 to 4 days (interquartile range, 4-3, P = .0135), and there was a cost savings of $7,275 per case, with no added harm.
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