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Thrombectomy in Childhood Stroke.

Peter B Sporns1, André Kemmling1,2, Uta Hanning3

  • 11 Institute of Clinical Radiology University Hospital of Muenster Germany.

Journal of the American Heart Association
|February 27, 2019
PubMed
Summary
This summary is machine-generated.

Mechanical thrombectomy is a safe and effective treatment for large intracranial vessel occlusions in children. This study shows good neurological outcomes for pediatric stroke patients treated with thrombectomy.

Keywords:
childhood strokeendovascular recanalizationischemic strokepediatric strokethrombectomy

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Area of Science:

  • Neurology
  • Pediatric Stroke
  • Interventional Neuroradiology

Background:

  • Efficacy of mechanical thrombectomy established in adults for large intracranial vessel occlusions.
  • Limited data exist on the safety and efficacy of thrombectomy in pediatric stroke patients.

Purpose of the Study:

  • To investigate the feasibility and clinical outcomes of mechanical thrombectomy in children with large-vessel occlusion.
  • To assess the safety and effectiveness of thrombectomy in the pediatric population.

Main Methods:

  • Retrospective analysis of 12 pediatric patients (<18 years) treated with mechanical thrombectomy at 3 German stroke centers.
  • Assessment of interventional results and clinical outcomes using the Pediatric National Institutes of Health Stroke Scale and modified Rankin Scale.

Main Results:

  • All patients achieved good angiographic outcomes (mTICI 2b or 3).
  • Significant improvement in neurological status observed, with a median Pediatric National Institutes of Health Stroke Scale of 3.5 at day 7 and a median modified Rankin Scale of 1.0 at 3 months.
  • No major periprocedural complications were reported.

Conclusions:

  • Mechanical thrombectomy is a safe procedure for treating childhood stroke.
  • Pediatric patients with large intracranial vessel occlusions treated with thrombectomy demonstrate favorable neurological outcomes.