Related Experiment Video
Updated: Jan 28, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
Mobile App-Based Intervention for Adolescents With First-Episode Psychosis: Study Protocol for a Pilot Randomized
Sara Barbeito1, Teresa Sánchez-Gutiérrez1, María Mayoral2
1Faculty of Health Sciences, Universidad Internacional de la Rioja (UNIR), Logroño, Spain.
This study tests a mobile app intervention to improve community functioning in adolescents with first-episode psychosis (FEP). The app aims to enhance quality of life and treatment adherence, potentially reducing relapses and hospitalizations.
Area of Science:
- Psychiatry and Mental Health
- Digital Health Interventions
- Adolescent Health
Background:
- First-episode psychosis (FEP) significantly impacts adolescents, affecting their community functioning and quality of life.
- Mobile app-based interventions show promise in improving treatment access and engagement for young patients with FEP.
- Early intervention in FEP is critical for long-term outcomes, including relapse prevention and rehospitalization rates.
Observation:
- This study protocol outlines a single-blind randomized clinical trial (RCT) for adolescents (14-19 years) with FEP.
- The intervention group receives standard care plus a mobile app with modules on psychoeducation, symptom recognition, problem-solving, mindfulness, and support.
- The control group receives standard care only.
Findings:
- The primary outcome is the reduction of psychotic and depressive symptoms.
- Secondary outcomes include treatment adherence, disease awareness, substance use, and quality of life.
- Data will be analyzed using an intention-to-treat (ITT) approach with mixed-effects models to assess group-by-time interactions.
Implications:
- This pilot RCT explores an innovative mobile app-based psychological intervention for adolescents with FEP during a critical developmental period.
- Findings could inform larger-scale studies and facilitate the broader adoption of digital therapeutics for FEP.
- Successful implementation may improve long-term outcomes, reduce healthcare burdens, and enhance the lives of young individuals experiencing psychosis.
More Related Videos
Related Concept Videos
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
Pilot and Numeric Relaying
Psychosis: Goals of Pharmacotherapy
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Cognitive Development During Adolescence

