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Improving Reproducibility in Synthetic Biology.
Mathew M Jessop-Fabre1, Nikolaus Sonnenschein1
1The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Frontiers in Bioengineering and Biotechnology
|February 27, 2019
Summary
Synthetic biology research faces reproducibility challenges. Emerging technologies like biofoundries and cloud labs offer solutions to enhance the quality and reliability of synthetic biology studies.
Area of Science:
- Synthetic biology
- Life sciences research
Background:
- Synthetic biology promises transformative technologies but faces significant hurdles.
- A key challenge is the lack of reproducibility in life sciences research.
- This issue is gaining community recognition, prompting the development of solutions.
Purpose of the Study:
- To outline emerging technologies that can improve reproducibility in synthetic biology.
- To discuss how automated facilities can enhance research quality.
- To explore potential transformations in synthetic biology research practices.
Main Methods:
- Perspective article outlining current technological developments.
- Discussion of automated facilities such as biofoundries and cloud labs.
- Identification of technologies aiding research quality and reproducibility.
Main Results:
- Automated facilities (biofoundries, cloud labs) are emerging as potential solutions.
- These technologies can improve the quality and reproducibility of synthetic biology work.
- Other developing technologies also show promise for transforming research.
Conclusions:
- Addressing reproducibility is crucial for synthetic biology to fulfill its potential.
- Emerging technologies, particularly automated facilities, offer pathways to improved research standards.
- These advancements are expected to transform synthetic biology research methodologies.
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