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Jowl Reduction With Deoxycholic Acid.

José Raúl Montes1, Elizabeth Santos1, Annirudha Chillar2

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Summary
This summary is machine-generated.

Deoxycholic acid (DCA) injections offer a safe and effective method for nonsurgical jowl fat reduction. This study demonstrates positive aesthetic improvements with minimal adverse events in patients seeking facial contouring.

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Area of Science:

  • Cosmetic Dermatology
  • Aesthetic Medicine
  • Injectable Treatments

Background:

  • Jowl fat is a common aesthetic concern.
  • Nonsurgical reduction methods are in demand.
  • Deoxycholic acid (DCA) is an injectable agent for fat dissolution.

Purpose of the Study:

  • To evaluate the safety and feasibility of deoxycholic acid (DCA) injections for targeting jowl fat.
  • To assess the efficacy of DCA for nonsurgical jowl reduction.

Main Methods:

  • Prospective study involving 12 patients with mild to moderate jowl fat.
  • Subcutaneous injection of DCA in a predefined area above the mandibular border.
  • Assessment of treatment response using physician and patient Global Aesthetic Improvement Scale (GAIS).

Main Results:

  • Significant aesthetic improvement observed in most treated jowls after initial DCA injections.
  • Further improvement noted in jowls receiving a second treatment session.
  • Common adverse events included edema, bruising, pain, and induration, generally mild and transient.

Conclusions:

  • Deoxycholic acid (DCA) injections represent a safe and effective option for nonsurgical jowl contouring.
  • The protocol demonstrated feasibility for reducing mild to moderate jowl fat.
  • Further research may explore optimal dosing and treatment intervals for enhanced outcomes.