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Updated: Jan 28, 2026

The ITS2 Database
Published on: March 12, 2012
Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer
Piotr Minkiewicz1, Marta Turło2, Anna Iwaniak3
1University of Warmia and Mazury in Olsztyn, Chair of Food Biochemistry, Plac Cieszyński 1, 10-726 Olsztyn-Kortowo, Poland. minkiew@uwm.edu.pl.
Abstract:
Diet is considered to be a significant factor in cancer prevention and therapy. Many food components reveal anticancer activity. The increasing number of experiments concerning the anticancer potential of chemical compounds, including food components, is a challenge for data searching. Specialized databases provide an opportunity to overcome this problem. Data concerning the anticancer activity of chemical compounds may be found in general databases of chemical compounds and databases of drugs, including specialized resources concerning anticancer compounds, databases of food components, and databases of individual groups of compounds, such as polyphenols or peptides. This brief review summarizes the state of knowledge of chemical databases containing information concerning natural anticancer compounds (e.g., from food). Additionally, the information about text- and structure-based search options and links between particular internet resources is provided in this paper. Examples of the application of databases in food and nutrition sciences are also presented with special attention to compounds that are interesting from the point of view of dietary cancer prevention. Simple examples of potential database search possibilities are also discussed.
Insights
Discovering natural anticancer compounds from food is crucial for cancer prevention. This review highlights chemical databases that help researchers easily find these dietary cancer-fighting agents.
Area of Science:
- Food science
- Oncology
- Bioinformatics
Background:
- Diet plays a vital role in cancer prevention and treatment.
- Numerous food components exhibit anticancer properties.
- The growing volume of research on anticancer compounds presents data-searching challenges.
Purpose of the Study:
- To review existing chemical databases for natural anticancer compounds found in food.
- To provide information on text- and structure-based search functionalities.
- To illustrate database applications in food science for dietary cancer prevention.
Main Methods:
- Literature review of specialized chemical databases.
- Analysis of search options (text- and structure-based).
- Identification of relevant databases for food components with anticancer activity.
Main Results:
- Several chemical databases contain information on natural anticancer compounds from food sources.
- Databases offer various search capabilities, including structure-based queries.
- Links between different internet resources facilitate comprehensive data retrieval.
Conclusions:
- Chemical databases are essential tools for efficiently searching for natural anticancer compounds in food.
- These resources support research in dietary cancer prevention by highlighting relevant compounds like polyphenols and peptides.
- Database applications aid in understanding the anticancer potential of food components.
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