Related Experiment Video
Updated: Jan 28, 2026
12:09
Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy
Published on: August 5, 2014
18.5K
Discordant attributes of structural and functional brain connectivity in a two-layer multiplex network
Sol Lim1,2, Filippo Radicchi3, Martijn P van den Heuvel4,5
1Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, 47405, USA. cogscisol@gmail.com.
Scientific Reports
|March 1, 2019
Summary
Structural connectivity (SC) in the brain is assortative, while functional connectivity (FC) is disassortative. These differing network organizations, particularly in the left hemisphere, may explain neurological dysfunction laterality.
Area of Science:
- Neuroscience
- Network Science
- Brain Imaging
Background:
- Functional connectivity (FC) and structural connectivity (SC) are known to be correlated.
- Limited research has explored the distinct network organizations of SC and FC and their interaction.
Purpose of the Study:
- To investigate the differences in network organization between SC and FC.
- To understand how these differences inform the mutual interaction between SC and FC.
- To explore the implications of these differences for brain function and dysfunction.
Main Methods:
- Utilized a multi-layer framework to construct a two-layer multiplex network of SC and FC.
- Employed Magnetic Resonance Imaging (MRI) data from the Human Connectome Project.
- Examined node strength assortativity within and between the SC and FC layers.
Main Results:
- SC generally exhibits assortative organization, connecting regions of similar node strengths.
- FC displays disassortative mixing, a pattern observed across individual resting-state networks.
- These patterns show lateralization, with FC disassortativity predominantly driven by the left hemisphere.
Conclusions:
- The discrepancy between SC assortativity and FC disassortativity highlights distinct network principles.
- Lateralized patterns of SC and FC associativity may offer insights into the laterality of neurological disorders.
- Understanding these network differences is crucial for comprehending brain function, dysfunction, and recovery.
More Related Videos
Related Concept Videos
01:21Layers of Connective Tissue Proper
3.5K
Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing...
3.5K
00:56Attribution Theory
13.8K
Behavior is a product of both the situation (e.g., cultural influences, social roles, and the presence of bystanders) and of the person (e.g., personality characteristics). Subfields of psychology tend to focus on one influence or behavior over others. Situationism is the view that our behavior and actions are determined by our immediate environment and surroundings. In contrast, dispositionism holds that our behavior is determined by internal factors (Heider, 1958).
13.8K
01:17Functions of Connective Tissues
16.4K
Connective tissues perform a broad range of functions in the body. Their primary function is to connect and link different tissues in the body and act as packaging material between tissues. The areolar tissue, a connective tissue prototype, commonly cements various tissue types in diverse body organs. In contrast, adipose tissue cushions internal organs while insulating the body from heat loss.
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
16.4K
01:14Fundamental Attribution Error
13.7K
According to some social psychologists, people tend to overemphasize internal factors as explanations—or attributions—for the behavior of other people. They tend to assume that the behavior of another person is a trait of that person, and to underestimate the power of the situation on the behavior of others. They tend to fail to recognize when the behavior of another is due to situational variables, and thus to the person’s state. This erroneous assumption is...
13.7K
01:56Structural Protein Function
29.9K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity. In bones and teeth, it mineralizes to...
29.9K
01:58Fruit Development, Structure, and Function
25.2K
Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
25.2K