Related Experiment Video
Updated: Jan 28, 2026

Modeling Chemotherapy Resistant Leukemia In Vitro
Published on: February 9, 2016
Impact of chemotherapy on subsequent generations
Biren V Patel1, James M Hotaling2
1Department of OB/GYN, University of Utah, Salt Lake City, UT.
Abstract:
Chemotherapy is extensively used in healthcare and its usage is only increasing. Since DNA and DNA modifiers (epigenetics) are altered by chemotherapy, the long-term effects in exposed individuals are important to clinicians and researchers. For example, animal studies have shown evidence of both genetic and epigenetic changes in progeny several generations downstream from the initial exposure. At present, there is extremely limited available research in humans but the study of the generational effects of chemotherapy could prove to be significant.
Related Concept Videos
Impact of Groups on Groups
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Impact
When particles with different initial velocities collide, they induce deformation by applying equal and opposite impulses. At the point of maximum deformation, the particles move together with...
Impact Loading
In cases of elastic deformation,...
Types of Impact
The coefficient of restitution is a metric for understanding the dynamics of impacts. It quantifies the ratio of relative velocity...
Impact: Problem Solving
By designating the launch point as the origin and utilizing kinematic equations, the vertical component of the projectile's velocity at the point of impact is...

