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Updated: Jan 28, 2026

Preparation and High-temperature Anti-adhesion Behavior of a Slippery Surface on Stainless Steel
Published on: March 29, 2018
Plasma nitriding under low temperature improves the endothelial cell biocompatibility of 316L stainless steel
Janine K F S Braz1, Gabriel M Martins1, Vladimir Sabino2
1Departamento de Ciências Animais, Universidade Federal Rural do Semi-Árido, UFERSA, Av. Francisco Mota, 572 -Bairro Costa e Silva, Mossoró, RN, CEP: 59.625-900, Brazil.
Objectives:
To evaluate the effects of the surface modification of 316L stainless steel (SS) by low-temperature plasma nitriding on endothelial cells for stent applications.
Results:
X-ray diffraction (XRD) confirmed the incorporation of nitrogen into the treated steel. The surface treatment significantly increased SS roughness and hydrophilic characteristics. After 4 h the cells adhered to the nitride surfaces and formed clusters. During the 24 h incubation period, cell viability on the nitrided surface was higher compared to the polished surface. Nitriding reduced late apoptosis of rabbit aorta endothelial cell (RAEC) on the SS surface.
Conclusion:
Low temperature plasma nitriding improved the biocompatible of stainless steel for use in stents.
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