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Phage-Mediated Genetic Manipulation of the Lyme Disease Spirochete Borrelia burgdorferi
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Pediatric Antibiotic-refractory Lyme Arthritis: A Multicenter Case-control Study.

Daniel B Horton1,2, Alysha J Taxter3,4, Amy L Davidow3,4

  • 1From the Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey; Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, New Brunswick, New Jersey; Department of Biostatistics - Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey; Department of Pediatrics, Brenner Children's Hospital, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina; Department of Pediatrics, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania; Department of Pediatrics, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Pediatrics, Nemours/A.I. duPont Hospital for Children, Thomas Jefferson University, Wilmington, Delaware. daniel.horton@rutgers.edu.

The Journal of Rheumatology
|March 3, 2019
PubMed
Summary

Older children with prolonged Lyme arthritis, especially in the knee, are at higher risk for antibiotic-refractory Lyme arthritis (ARLA). Prompt anti-inflammatory treatment is recommended for persistent cases.

Keywords:
EPIDEMIOLOGIC STUDIESLYME ARTHRITISPEDIATRIC ARTHRITISRISK FACTORS

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