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Concurrent exercise training on hyperglycemia and comorbidities associated: Non-responders using clinical cutoff
Cristian Álvarez1,2, Rodrigo Ramírez-Campillo1,2, Alejandro Lucia3
1Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile.
Scandinavian Journal of Medicine & Science in Sports
|March 3, 2019
Summary
Concurrent training (CT) improved cardiovascular risk factors in women with hyperglycemia, reducing abdominal obesity and improving lipid profiles. However, individual responses varied, with a notable percentage showing no change or adverse effects in body composition, blood pressure, or lipids.
Area of Science:
- Exercise Physiology
- Cardiovascular Health
- Metabolic Disorders
Background:
- Hyperglycemia is a significant risk factor for cardiovascular disease.
- Concurrent training (CT), combining resistance and endurance exercise, is a potential intervention for managing cardiovascular risk.
- Understanding individual responses to CT is crucial for personalized exercise prescription.
Purpose of the Study:
- To investigate the effects of a 20-week CT intervention on cardiovascular risk factors in adult women with hyperglycemia.
- To determine the prevalence of non-responders to CT for various cardiovascular outcomes.
Main Methods:
- Physically inactive, overweight/obese, hyperglycemic women were randomized into a 20-week CT group or a control group.
- Cardiovascular risk factors including body composition, blood pressure, and lipid profiles were measured pre- and post-intervention.
- Non-responder prevalence was analyzed for body composition, blood pressure, and lipid profiles.
Main Results:
- CT significantly reduced waist circumference and improved lipid profiles in hyperglycemic women on average.
- Individual analysis revealed shifts in cardiovascular risk status for waist circumference, blood pressure, and lipid profiles.
- Approximately 30% showed no change/adverse response in body composition, 50% for blood pressure, and 20% for lipid profiles.
Conclusions:
- A 20-week CT intervention can reduce abdominal obesity and improve cardiovascular risk factors in adult women with hyperglycemia.
- Significant inter-individual variability exists in response to CT, highlighting the need for personalized approaches.
- A considerable proportion of individuals may not respond favorably to CT, necessitating further research into non-responder characteristics.
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