Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.4K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.4K
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

2.8K
2.8K
Storage01:23

Storage

402
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
402
Conservation of Protein Domains Over Different Proteins02:26

Conservation of Protein Domains Over Different Proteins

14.4K
Protein domains are small structurally independent units that are part of a single amino acid chain.  Although these domains are often structurally independent, they may rely on synergistic effects to perform their functions as part of a larger protein. Protein domains may be conserved within the same organism, as well as across different organisms.
A limited set of protein domains often duplicate and recombine during evolution. These domains can be organized in different combinations to...
14.4K
The Intrinsic Apoptotic Pathway01:31

The Intrinsic Apoptotic Pathway

8.5K
Internal cellular stress, such as cellular injury or hypoxia, triggers intrinsic apoptosis. The B-cell lymphoma 2 (Bcl-2) family of proteins are the primary regulators of the intrinsic apoptotic pathway. For example, during DNA damage, checkpoint proteins, such as Ataxia Telangiectasia Mutated (ATM protein) and Checkpoints Factor-2 (Chk2) proteins, are activated. These proteins phosphorylate p53 which further activates pro-apoptotic proteins, such as Bax, Bak, PUMA, and Noxa, and inhibits...
8.5K
Extrinsic and Intrinsic Pathways of Hemostasis01:20

Extrinsic and Intrinsic Pathways of Hemostasis

12.6K
Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
12.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Articulatory rehearsal modulates word frequency effect in working memory tasks.

Journal of experimental psychology. Learning, memory, and cognition·2026
Same author

Depressive symptoms and functional dependence in near-centenarians and centenarians: a scoping review.

BMC geriatrics·2026
Same author

Assessing the involvement of long-term memory in working memory.

Psychonomic bulletin & review·2026
Same author

Does the Experimenter Presence Affect Verbal Working Memory?

Journal of cognition·2025
Same author

Super-Recognizers, or Su-Perceivers? Insights from fast periodic visual stimulation (FPVS) EEG.

Brain topography·2025
Same author

Different measures of working memory decline at different rates across adult ageing and dual task costs plateau in mid-life.

Quarterly journal of experimental psychology (2006)·2025
Same journal

Executive function and social behavior: Causal evidence from loading working memory and inhibitory control.

Journal of experimental psychology. General·2026
Same journal

Correction to "Your research is public engagement: A case for more intentional science communication in research with human subjects" by Vaughn (2026).

Journal of experimental psychology. General·2026
Same journal

Correction to "Costs and benefits of acting extraverted: A randomized controlled trial" by Jacques-Hamilton et al. (2019).

Journal of experimental psychology. General·2026
Same journal

Conveying (discrete) emotionality with novel words.

Journal of experimental psychology. General·2026
Same journal

Physical actions shape moral choices: Environment-directed movements reduce cheating in young children.

Journal of experimental psychology. General·2026
Same journal

From chunks to schemas: Learning in the Hebb repetition paradigm.

Journal of experimental psychology. General·2026
See all related articles

Related Experiment Video

Updated: Jan 28, 2026

Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging
11:24

Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging

Published on: December 12, 2012

14.0K

Is working memory storage intrinsically domain-specific?

Kim Uittenhove1, Lina Chaabi2, Valérie Camos2

  • 1Faculty of Psychology and Educational Sciences, University of Geneva.

Journal of Experimental Psychology. General
|March 5, 2019
PubMed
Summary
This summary is machine-generated.

Working memory (WM) is not strictly domain-specific. Concurrent auditory-verbal and visuospatial tasks interfere, challenging previous claims of domain independence in working memory storage.

More Related Videos

A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K
Quasi-light Storage for Optical Data Packets
07:45

Quasi-light Storage for Optical Data Packets

Published on: February 6, 2014

11.3K

Related Experiment Videos

Last Updated: Jan 28, 2026

Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging
11:24

Targeted Labeling of Neurons in a Specific Functional Micro-domain of the Neocortex by Combining Intrinsic Signal and Two-photon Imaging

Published on: December 12, 2012

14.0K
A Real-world What-Where-When Memory Test
09:13

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

12.1K
Quasi-light Storage for Optical Data Packets
07:45

Quasi-light Storage for Optical Data Packets

Published on: February 6, 2014

11.3K

Area of Science:

  • Cognitive Psychology
  • Neuroscience

Background:

  • Recent research suggested working memory (WM) storage is domain-specific, showing no dual-task costs when combining auditory and visuospatial memory sets.
  • This implies separate neural resources for different sensory modalities in WM.

Purpose of the Study:

  • To investigate the domain specificity of working memory (WM) storage using a paradigm that manipulates auditory-verbal and visuospatial memory loads.
  • To compare the effects of recognition versus recall procedures on detecting interference between verbal and visuospatial WM.

Main Methods:

  • Participants concurrently maintained auditory-verbal memory sets (letters) and visuospatial memory sets (dots in space) at varying load levels.
  • A probe-recognition procedure and a recall procedure were employed to assess memory performance.
  • Concurrent articulation was optionally used to control for subvocal rehearsal.

Main Results:

  • The probe-recognition procedure replicated the absence of dual-task costs, supporting domain specificity.
  • However, the recall procedure revealed significant interference between auditory-verbal and visuospatial working memory.
  • Increased verbal load impaired visuospatial recall, and vice versa, irrespective of concurrent articulation.

Conclusions:

  • Working memory (WM) storage demonstrates significant between-domain interference, particularly when assessed via recall, challenging the notion of strict domain specificity.
  • The findings highlight the critical role of the assessment method (recognition vs. recall) in understanding WM structure and function.
  • These results have implications for models of working memory capacity and the interaction between verbal and visuospatial processing.