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Updated: Jan 28, 2026

A Neonatal Mouse Spinal Cord Compression Injury Model
Published on: March 27, 2016
Minimal variation of the plasma lipidome after delayed processing of neonatal cord blood
John M Wentworth1,2, Naiara G Bediaga3,4, Megan A S Penno5
1Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia. wentworth@wehi.edu.au.
Background:
Cord blood lipids are potential disease biomarkers. We aimed to determine if their concentrations were affected by delayed blood processing.
Method:
Refrigerated cord blood from six healthy newborns was centrifuged every 12 h for 4 days. Plasma lipids were analysed by liquid chromatography/mass spectroscopy.
Results:
Of 262 lipids identified, only eight varied significantly over time. These comprised three dihexosylceramides, two phosphatidylserines and two phosphatidylethanolamines whose relative concentrations increased and one sphingomyelin that decreased.
Conclusion:
Delay in separation of plasma from refrigerated cord blood has minimal effect overall on the plasma lipidome.
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