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Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
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Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

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Discovery of NR2B-selective antagonists via scaffold hopping and pharmacokinetic profile optimization

Kosuke Anan1, Moriyasu Masui1, Aya Tazawa1

  • 1Medicinal Chemistry Research Laboratory, Shionogi & Co., Ltd, 1-1 Futabacho, 3-chome, Toyonaka 561-0825, Japan.

Bioorganic & Medicinal Chemistry Letters
|March 6, 2019
PubMed

Keywords:
Analgesic activityNMDA receptor antagonistScaffold hopping

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