Effects of camera-based mirror visual feedback therapy for patients who had a stroke and the neural mechanisms...

As a combination of visual stimulation and motor imagery, mirror visual feedback (MVF) is an effective treatment for motor impairment after stroke; however, few studies have investigated its effects on relevant cognitive processes such as visual perception and motor imagery. Camera-based MVF (camMVF) overcomes the intrinsic limitations of real mirrors and is recognised as an optimal setup. This study aims to investigate the effects of camMVF as an adjunct treatment for stroke patients, compare camMVF outcomes with those of conventional therapy and elucidate neural mechanisms through which MVF influences cognition and brain networks.

This will be a multicentre, single-blinded, randomised controlled trial including 90 patients randomised into three groups: camera-based mirror visual feedback intervention group (30), shielded mirror visual feedback intervention group (30) and conventional group (30). Patients in each group will receive a 60 min intervention 5 days per week over 4 weeks. The primary outcome will be the Fugl-Meyer Assessment Upper Limb subscale measurement. Secondary outcomes include the modified Ashworth Scale, Grip Strength test, Modified Barthel Index, Functional Independence Measure, Berg Balance Scale, 10-metre walking test, hand-laterality task and electroencephalography .

Ethics approval was granted by the Huashan Hospital Institutional Review Board on 15 March (KY2017-230). We plan to submit the results to a peer-reviewed journal and present them at conferences, rehabilitation forums and to the general public.

ChiCTR-INR-17013644; Pre-results.