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Updated: Jan 28, 2026

Drawing Blood from Rats through the Saphenous Vein and by Cardiac Puncture
Published on: August 23, 2007
Drawing blood cultures through intravascular catheters: Controversy and update
1Department of Medicine,Warren Alpert Medical School of Brown University,Providence, Rhode Island.
Abstract:
Studies published between 1999 and 2011 demonstrated increased blood culture contamination with catheter-drawn cultures compared with percutaneously-drawn cultures. Studies published between 2012 and 2015 reported that use of antiseptic barrier caps on central venous catheter hubs significantly reduces the incidence of catheter-drawn blood culture contamination. Local guidelines regarding sites for blood culture collection should reflect institution-level blood culture contamination rates for percutaneously-drawn and catheter-drawn cultures using currently available technologies that reduce contamination at both sites.
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