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Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

2.1K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.1K
The Tongue and Taste Buds00:49

The Tongue and Taste Buds

41.0K
The surface of the tongue is covered with various small bumps called papillae, which either distribute what has been ingested (filiform papillae) or contain the sensory taste (or gustatory) receptor cells (fungiform, circumvallate, and foliate papillae). Embedded within each taste-related papilla are the taste buds—clusters of 30 to 100 gustatory receptor cells.
41.0K
Taste Buds and Receptors01:20

Taste Buds and Receptors

5.2K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
5.2K
Bode Plots Construction01:24

Bode Plots Construction

1.1K
The Bode plot is an essential tool in control system analysis, mapping the frequency response of a system through a magnitude plot and a phase plot, both against a logarithmic frequency axis. To construct a Bode plot, consider the transfer function H(ω):
1.1K
Construction of Root Locus01:15

Construction of Root Locus

415
The construction of a root locus involves several key steps to analyze and visualize the behavior of a system's poles with varying gain. The number of branches in the root locus equals the number of closed-loop poles and is symmetrical about the real axis.
For positive gain values, the root locus exists on the real axis to the left of an odd number of finite open-loop poles or zeros. The root locus starts at the open-loop poles and traces the paths of the closed-loop poles as the gain...
415
Construction of Frequency Distribution01:15

Construction of Frequency Distribution

12.7K
A frequency distribution table can be constructed using the steps given below.
First, make a table with two columns—one with the title of the data that needs to be organized, and the other column for frequency. [Draw a third column for tally marks if needed]. Then, take a look at the items given in the data set and decide if an ungrouped frequency distribution table or a grouped frequency distribution table would be more suitable. If there are large sets of different values, then it is...
12.7K

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Updated: Jan 28, 2026

Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink
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Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink

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Bioengineering Tooth Bud Constructs Using GelMA Hydrogel.

Elizabeth E Smith1, Pamela C Yelick2

  • 1Department of Cell, Molecular, and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University School Medicine, Boston, MA, USA.

Methods in Molecular Biology (Clifton, N.J.)
|March 7, 2019
PubMed
Summary
This summary is machine-generated.

Researchers developed a novel bioengineered tooth bud model, offering a biological alternative to artificial dental implants. This advancement paves the way for future clinical applications in regenerative dentistry.

Keywords:
Hydrogel scaffoldsOdontogenesisPrimary dental cell cultureTooth tissue engineering

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Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Dental Research

Background:

  • Current artificial dental implants lack biological integration and can be functionally surpassed by natural teeth.
  • There is a significant clinical need for biologically based alternatives in restorative dentistry.

Purpose of the Study:

  • To establish a novel bioengineered tooth bud model for potential clinical applications in dentistry.
  • To describe the methods for fabricating and analyzing bioengineered tooth tissues.

Main Methods:

  • Isolation of dental cells.
  • Fabrication of a bioengineered tooth bud model.
  • In vivo implantation and post-harvest tissue analysis.

Main Results:

  • Successful establishment of a bioengineered tooth bud model.
  • Demonstration of methods for tissue fabrication and analysis.

Conclusions:

  • The developed bioengineered tooth bud model shows promise as a biologically based alternative for dental applications.
  • Further research and development are needed for clinical translation of bioengineered teeth.